After running a few of these in various locations, it turns out that:
Financial returns are currently between one and three dollars per day at best.
In addition to a high-end RTX GPU, you need a beefy CPU, at least 32GB of RAM, an SSD with ample free storage, and an Ethernet connection (not Wi-Fi) to an internet line with unlimited bandwidth and an upload speed of at least 100Mbps to have any hope of receiving deployments.
Such an investment isn't justified given the expected returns. However, if you have this kind of hardware for your own needs (gaming, video editing, etc.) and use it only one-third of the time—with the machine turned off the rest of the time—then it might be worth to do it.
Set up a dual-boot system with two SSDs: one running the operating system of your choice for personal or professional use, and the other running a bare-metal Ubuntu Linux system. This way, there’s no risk of one system compromising the other.
During deployment, the machine starts to heat up like a toaster. It is advisable to use water cooling for the CPU and GPU to reduce the risk of fire and ensure the equipment’s longevity.